Cybec 400 Adverse Reactions

Infections and infestations: Common: Bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection.
Uncommon: Pharyngitis, rhinitis.
Blood and lymphatic system disorders: Uncommon: Anaemia.
Rare: Thrombocytopenia, leukopenia.
Very rare: Pancytopenia.
Immune system disorders: Common: Hypersensitivity.
Very rare: Anaphylactic reaction.
Metabolism and nutrition disorders: Uncommon: Hyperkalaemia.
Psychiatric disorders: Common: Insomnia.
Uncommon: Anxiety, depression, fatigue.
Rare: Confusional state, hallucination.
Nervous system disorders: Common: Dizziness, hypertonia, headache.
Uncommon: Somnolence, cerebral infarction, paraesthesia.
Rare: Ataxia, dysgeusia.
Very rare: Cerebral haemorrhage, meningitis aseptic, ageusia, anosmia, epilepsy.
Eye disorders: Uncommon: Vision blurred, conjunctivitis.
Rare: Eye haemorrhage.
Very rare: Retinal artery occlusion, retinal vein occlusion.
Ear and labyrinth disorders: Uncommon: Tinnitus, hypoacusis.
Cardiac disorders: Common: Myocardial infarction.
Uncommon: Palpitations, congestive cardiac failure, tachycardia.
Rare: Arrhythmia.
Vascular disorder: Very common: Hypertension (including aggravated hypertension).
Rare: Flushing.
Very rare: Vasculitis.
Respiratory, thoracic and mediastinal disorders: Common: Cough, dyspnoea.
Uncommon: Bronchospasm.
Rare: Pulmonary embolism, pneumonitis.
Gastrointestinal disorders: Common: Vomiting, abdominal pain, diarrhoea, dyspepsia, flatulence, nausea, dysphagia.
Uncommon: Gastric ulcer, tooth disorder, constipation, gastritis, stomatitis, eructation, gastrointestinal inflammation.
Rare: Duodenal ulcer, oesophageal ulcer, gastrointestinal haemorrhage, intestinal ulcer, large intestinal ulcer, intestinal perforation, pancreatitis, oesophagitis, melaena, colitis.
Hepatobiliary disorders: Uncommon: Hepatic enzyme increased (includes alanine aminotransferase increased and aspartate aminotransferase increased), abnormal hepatic function.
Rare: Hepatitis.
Very rare: Hepatic failure, hepatitis fulminant, hepatic necrosis, cholestasis, hepatitis cholestatic, jaundice.
Skin and subcutaneous tissue disorders: Common: Pruritus (includes pruritus generalized), rash.
Uncommon: Urticaria, ecchymosis.
Rare: Angioedema, alopecia, photosensitivity reaction.
Very rare: Dermatitis bullous, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), dermatitis exfoliative.
Musculoskeletal and connective tissue disorders: Common: Arthralgia.
Uncommon: Muscle spasms (leg cramps).
Very rare: Myositis.
Renal and urinary disorders: Uncommon: Blood creatinine increased, blood urea increased.
Rare: Renal failure acute, hyponatraemia.
Very rare: Tubulointerstitial nephritis, nephrotic syndrome, glomerulonephritis minimal lesion.
Reproductive system and breast disorders: Rare: Menstrual disorder.
Not known: Infertility female (female fertility decreased).
General disorders and administration site conditions: Common: Influenza like illness, oedema peripheral.
Uncommon: Face oedema, chest pain.
Injury, poisoning and procedural conditions: Common: Injury.